Vitamin B2 is a water-soluble vitamin needed to process amino acids and fats, activate vitamin B6 and folic acid, and help convert carbohydrates into the
fuel the body runs on—adenosine triphosphate (ATP). Under some conditions, vitamin B2
can act as an antioxidant.
Reliable
and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal
or no scientific evidence. For a supplement, little scientific support and/or minimal health
benefit.
Who is likely to be deficient?
Vitamin B2 deficiency can occur in
alcoholics. Also, a deficiency may be more likely in people with cataracts12 or sickle cell anemia.3 In developing
countries, vitamin B2 deficiency has been found to be a risk factor for the development of preeclampsia in pregnant women.4 People with chronic fatigue syndrome may be deficient in vitamin
B2.5
How much is usually taken?
The ideal level of intake is not known. The amounts found in many multivitamin supplements (20–25 mg) are more
than adequate for most people.
Are there any side effects or interactions?
At supplemental and dietary levels, vitamin B2 is nontoxic.
Are there any drug
interactions?
Certain medicines may interact with vitamin B2. Refer to drug interactions for a list of those medicines.
References (To view, roll mouse over the "References" heading; to hide, click on the heading)
1. Bhat KS. Nutritional status of thiamine, riboflavin and pyridoxine in
cataract patients. Nutr Rep Int 1987;36:685–92.
2. Prchal JT, Conrad ME, Skalka HW. Association of presenile cataracts
with heterozygosity for galactosaemic states and with riboflavin deficiency. Lancet
1978;1:12–3.
3. Varma RN, Mankad VN, Phelps DD, et al. Depressed erythrocyte
glutathione reductase activity in sickle cell disease. Am J Clin Nutr
1983;38:884–7.
4. Wacker J, Fruhauf J, Schulz M, et al. Riboflavin deficiency and
preeclampsia. Obstet Gynecol 2000;96:38–44.
5. Heap LC, Peters TJ, Wessely S. Vitamin B status in patients with
chronic fatigue syndrome. J R Soc Med 1999;92:183–5.
The information presented in Aisle7 is for informational purposes only.
It is based on scientific studies (human, animal, or in vitro), clinical experience,
or traditional usage as cited in each article. The results reported may not necessarily occur
in all individuals. For many of the conditions discussed, treatment with prescription or over
the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist
for any health problem and before using any supplements or before making any changes in
prescribed medications.
